Clinical:Diabetic nephropathy
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Diabetic nephropathies are "kidney injuries associated with diabetes mellitus and affecting kidney glomerulus; arterioles; kidney tubules; and the interstitium. Clinical signs include persistent proteinuria, from microalbuminuria progressing to albuminuria of greater than 300 mg/24 h, leading to reduced glomerular filtration rate and end-stage renal disease."[1]
Diabetic nephropathy is also called Kimmelstiel-Wilson Disease and glomerulosclerosis.
Prevention
Angiotensin II type 1 receptor blockers
Telmisartan slowed the increase in albuminuria but is associated with doubling of serum creatinine and reduction in estimated glomerular filtration rate.[2]
References
- ↑ Anonymous, (2009) Diabetic nephropathy (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Mann, Johannes F E et. al. "Effect of telmisartan on renal outcomes: a randomized trial." Annals of internal medicine 151 (2009): 1-10, W1-2 - Abstract
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