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Complete Transposition of the Great Vessels
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Important Resources for Complete Transposition of the Great Vessels:
Complete transposition of the great vessels is relatively common, accounting for about 5% of congenital heart disease. It is the most common cause of "blue newborn". Early surgery is usually required.
Complete transposition is characterized by malformation of the cardiac outflow tract so that the left ventricle leads to the pulmonary trunk, and the right ventricle leads to the aorta. This malformation is caused by abnormal formation of the aorticopulmonary septum such that the septum does not form a normal spiral.
A shunt is required for compatiblity with life. Otherwise, all the oxygenated blood is returned to the lungs and the deoxygenated blood bypasses the lungs. Shunts allow mixing of oxygenated and deoxygenated blood. Patients with a ventricular septal defect (VSD) (35%) have a stable shunt. Patients with only a patent foramen ovale or patent ductus arteriosus (PDA) (65%) have unstable shunts that tend to close.
Other Names
- dextro-Transposition of the great arteries (d-TGA)
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