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Imperforate Hymen
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The hymen displays marked variation in form including the nature of developmentally formed perforations. Generally, only imperforate hymen is clinically significant. The incidence of imperforate hymen may be as high as 1 in 1000 newborn females. The typical presentation of uncorrected imperforate hymen is cyclic abdominal pain and hematocolpos (sequestration of menstrual blood in the vagina) in a young adolescent woman. Imperforate hymen is caused by a failure of canalization of the hymen. The lower vagina is formed by canalization of the vaginal plate in the second trimester, and perforation of the hymen near the caudal end of the lower vagina usually occurs in the perinatal period.
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