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Influenza H5N1 (Bird Flu) Viral Sequences Isolated from Patients

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Contents

Sequences From GenBank and The Influenza Sequence Database

  • Cambodia
  • Patient not described
  • Viral sequences
A/Cambodia/JP52a/2005
PB2 | PB1| PA | HA| NP | NA | M | NS
  • China (Hong Kong)
  • Patient: 13 year old boy
  • Patient died in 1997
  • Viral sequences
A/Hong Kong/483/97
PB2 | PB1| PA | HA | NP | NA | M | NS
  • References 2,3
  • Patient: 5 year old girl
  • Patient recovered in 1997
  • Viral sequences
A/Hong Kong/486/97
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • References 2,3
  • Patient: 33 year old man
  • February 07, 2003. Became ill.
  • February 14, 2003. Virus isolated from nasopharyngeal aspirate.
  • February 17, 2003. Patient died.
  • Patient was the father of the 9 year old boy described below.
  • Viral sequences
A/HK/212/03
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • References 1
  • Patient: 9 year old boy
  • February 09, 2004. Became ill.
  • February 14, 2003. Virus isolated from nasopharyngeal aspirate. Recovered.
  • Viral sequences
A/HK/213/03
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • References 1
  • Patient: 19 year old woman
  • Patient recovered
  • Viral sequences
A/Hong Kong/542/97
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • References 10, 11
  • Patient: 3 year old boy
  • Patient recovered
  • Viral sequences
A/Hong Kong/538/97
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • References 10, 11
  • Patient: 14 year old girl
  • Patient recovered
  • isolated from nasopharyngeal swab/tracheal aspirate
  • Viral sequences
A/Hong Kong/532/97
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • References 10, 11
  • Patient: 2 year old boy
  • Patient recovered
  • Viral sequences
A/Hong Kong/481/97
Bender et al sequences
PB2 | PB1 | PA | HA | NP | NA | M | NS
Hiromoto et al sequences
PB2 | PB1 | PA | HA | NP | NA | M | NS
Shaw et al sequences
PB2 | PB1 | PA | HA | NP | NA | M | NS
Lin et al sequences
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient: 60 year old woman
  • Patinet died
  • Viral sequences
A/Hong Kong/516/97
PB2 | PB1 | PA | HA | NP* | NA* | M | NS
  • References 10, 11
  • one of several sequences for this gene and strain
  • China (mainland)
  • Patients: Two women became ill and died in November 2005 in Anhui. One was 24 and the other 35 years old.
  • Viral sequences. No indication of which woman each virus was isolated from.
A/Anhui/1/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
A/Anhui/2/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral Sequences
A/human/Zhejiang/16/2006
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral Sequence
A/Guangxi/1/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Djibouti
  • Patient: 8 year old girl
  • No futher information available
  • Viral sequences
A/Djibouti/5691NAMRU3/2006
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Egypt
  • Patient: 30 year old man
  • Patient became ill in 2006.
  • Viral sequences
A/Egypt/2782-NAMRU3/2006
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Indonesia
  • Patient: 38 year old man
  • July 02, 2005. Patient became ill.
  • July 12, 2005. Patient died.
  • Viral sequences
A/Indonesia/5/05
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Iraq
  • Patient: 15 year old girl
  • February 17, 2006. Patient died.
  • Viral sequences
A/human/Iraq/207-NAMRU3/2006
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Thailand
  • Patient: 7 year old boy
  • Patient died in 2004
  • Viral sequences
A/Thailand/16/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • References 2,3
  • Patient: 58 year old woman
  • Patient died in 2004
  • Viral sequences
A/Thailand/3(SP-83)/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
References 2,3
  • Patient: 6 year old boy
  • Patient died in 2004
  • Viral sequences
A/Thailand/Kan353/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
References 2,3
  • Patient: Not described
  • Viral sequences
A/Thailand/676/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient: 5 year old boy
  • November 28, 2005. Patient became ill
  • December 07, 2005. Patient died
  • Viral sequences
A/Thailand/NK165/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Reference 6
  • Turkey
  • Patient not described
  • Viral sequences
A/Turkey/12/2006
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Turkey/15/06
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
  • A/Turkey/651242/06
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Turkey/65596/06
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Viet Nam
  • Patient: 10 year old boy
  • Patient died in 2004
  • Viral sequences
A/Viet Nam/1203/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • A/Vietnam/1204/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
References 2,3
  • Patient not described
  • Viral sequences
A/Hanoi/03/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
Viet Nam/3046/2004
B2 | PB1 | PA | HA | NP | NA | M | NS
eference 3
  • Patient not described
  • Viral sequences
A/Viet Nam/3062/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
Reference 3
  • Patient not described
  • Viral sequences
/Viet Nam/3212/2004
B2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
Viral sequences
A/Hatay/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient: 14 year old girl
  • February 22, 2005. Became ill.
  • February 27, 2005. Virus isolated from the patient
  • March 14, 2005. Patient discharged from the hospital.
  • Viral sequences
A/Hanoi/30408/2005
PB2 | PB1| PA | HA | NP | NA | M | NS
References 4
  • Patient not described
  • Viral sequences
A/Viet Nam/BL-014/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Viet Nam/HG-207/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Viet Nam/HN30408/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Viet Nam/JP14/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Viet Nam/JP4207/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Viet Nam/JPHN30321/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Viet Nam/LA-028/200
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Viet Nam/VL-020/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient not described
  • Viral sequences
A/Vietnam/CL105/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
Patient: 26 year old woman from Ho Chi Minh.
  • Patient died on August 5, 2005
  • Viral sequences
A/Vietnam/CL115/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
References 7, 8
  • Patient: 35 year old woman from Dong Thap.
  • January 14, 2005. Became ill.
  • January 21, 2005. Patient died.
  • Patient was the mother of the 13 year old girl from whom A/Vietnam/CL2009/2005 was isolated.
  • Viral sequences
A/Vietnam/CL119/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
References 7, 8
  • Patient: 13 year old girl from Dong Thap.
  • January 21, 2005. Became ill.
  • January 28, 2005. Patient died.
  • Patient was the daughter of the 35 year old woman from whom A/Vietnam/CL119/2005 was isolated.
  • Viral sequences
A/Vietnam/CL2009/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
References 7, 8
  • Patient not described
  • Viral sequences
A/Viet Nam/DT-036/2005
PB2 | PB1 | PA | HA | NP | NA | M | NS
  • Patient: 23 year old male from Lam Dong
  • January 2004. Recovered.
  • Viral sequences
A/Vietnam/CL26/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS
References 7, 8, 9
  • Patient: 8 year old girl from Ho Chi Minh City
  • January 2004. Recovered.
  • Viral sequences
A/Vietnam/CL01/2004
PB2 | PB1 | PA | HA | NP | NA | M | NS

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References

  • Guan, Y. (2004) H5N1 influenza: A protean pandemic threat. PNAS. 101: 8156–8161. Link
  • Maines et al. (2005) Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals. J. Virol. 79: 11788–11800. Link
  • Li et al. (2004) Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia. Nature. 430: 209–213. Link
  • Le et al. (2005) Isolation of drug-resistant H5N1 virus. Nature. 437: 1108. Link
  • Lin et al. (2000) Avian-to-human transmission of H9N2 subtype influenza A viruses: Relationship between H9N2 and H5N1 human isolates. PNAS. 97: 9654–9658. Link
  • Chutinimitkul et al. (2006) H5N1 Influenza A Virus and Infected Human Plasma. Emerging Infectious Diseases. 12: 1041–1043. Link
  • Smith et al. (2006) Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam. Virology. 350: 258–268. Link
  • de Jong et al. (2005) Oseltamivir Resistance during Treatment of Influenza A (H5N1) Infection. NEJM. 353: 2667–2672. Link
  • Tran et al. (2004) Avian Influenza A (H5N1) in 10 Patients in Vietnam. NEJM. 350:1179–1188. Link
  • Bender et al. (1999) Characterization of the surface proteins of influenza A (H5N1) viruses isolated from humans in 1997–1998. Virology. 254: 115–123. Link
  • Shaw et al. (2002) Molecular changes associated with the transmission of avian influenza a H5N1 and H9N2 viruses to humans. J. Med. Virol. 66: 107–114. Link

See also Clinical:Influenza H5N1 Hemagglutin Sequences

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