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Intestinal Atresias and Stenoses
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Important Resources for Intestinal Atresias and Stenoses:
Atresias and stenoses of the intestines occur in about 1/1500 births. Most occur in the duodenum. Atresias (absence of a lumen) account for 95% of cases; stenosis (narrowing of the lumen) occurs in 5%.
Duodenal Stenosis and Atresia
Duodenal atresias and stenoses are probably due to a defect in recanalization. During the 2nd month, the duodenal lumen is temporarily obliterated by proliferation of epithelial cells. The duodenum is normally recanalized by the end of the embryonic period.
Atresias and stenoses of other regions of the small and large intestines
Most other bowel atresias and stenoses are probably due to "fetal vascular accidents", sometimes secondary to malrotation, volvulus, gastroschisis, or omphalocele. Many of these bowel atresias could also be described as bowel aplasias because the bowel itself is discontinuous.
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