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Price Comparison of Antidiabetic Drugs

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Price of Glucose Lowering Oral Medication

Dose and Price of Diabetes Pills
Generic Name[1]Brand NameDose[2]Price for 1-Month Supply[3]
GenericBrand
Biguanides
MetforminGlucophage®500 mg once a day
500 mg twice a day
850 mg twice a day
1000 mg twice a day
$20
$40
$70
$85
$30

$60
$95
$120
Glucophage XR® 1000 mg once a day
2000 mg once a day
$45
$90
$60
$115
Second-generation sulfonylureas
Glimepiride Amaryl®1 mg once a day
2 mg once a day
4 mg once a day
8 mg once a day
$10
$20
$35
$75
$15
$25
$45
$85
GlipizideGlucotrol®5 mg once a day
10 mg once a day
10 mg twice a day
20 mg twice a day
$10
$20
$40
$75
$15
$30
$60
$125
Glucotrol XL®5 mg once a day
20 mg once a day
$10
$50
$15
$65
GlyburideDiabeta®, Micronase® 2.5 mg twice a day
5 mg once a day
5 mg twice a day
$30
$25
$45
$35
$30
$65
Glynase PresTab®1.5 mg once a day
3 mg once a day
6 mg twice a day
$10
$20
$60
$20
$35
$115
Thiazolidinediones
PioglitazoneActos®15 mg once a day
30 mg once a day
45 mg once a day
NA
NA
NA
$115
$190
$205
RosiglitazoneAvandia®2 mg twice a day
4 mg once a day
8 mg once a day
NA
NA
NA
$145
$110
$200
Meglitinides (taken before meals)
RepaglinidePrandin®0.5 mg three times a day
1 mg three times a day
4 mg three times a day
NA
NA
NA
$130
$130
$265
NateglinideStarlix®60 mg three times a day
120 mg three times a day
NA
NA
$130
$135
Alpha-glucosidase inhibitors (taken with meals)
AcarbosePrecose®25 mg three times a day
50 mg three times a day
100 mg three times a day
NA
NA
NA
$80
$85
$105
MiglitolGlyset®25 mg three times a day
50 mg three times a day
100 mg three times a day
NA
NA
NA
$75
$85
$95
Combination Pills
Glyburide/ metforminGlucovance®2.5 mg/500 mg twice a day
5 mg/500 mg twice a day
$65
$65
$75
$75
Glimepiride/ rosiglitazoneAvandaryl®2 mg/4 mg once a day
4 mg/4 mg once a day
NA
NA
$120
$120
Metformin/ rosiglitazoneAvandamet®500 mg/4 mg twice a day
1000 mg/2 mg twice a day
NA
NA
$220
$130
Metformin/ pioglitazoneActoplus Met®500 mg/15 mg twice a day
850 mg/15 mg twice a day
NA
NA
$180
$180
  1. These drugs were included in the research studies.
  2. Doses are similar to those used in the research studies.
  3. Average Wholesale Price from Drug Topics Red Book, 2007.
    XL/XR= extended release, NA = not available as generic.

Price of Insulin

Insulin comes in vials and pens. There are more units of insulin in one package of pens than in one vial.

Generic name1 Brand Name Price2
One Vial
(1,000 units)
Five-Pack Pens
(1,500 units)
Covers all through the day
Intermediate-Acting Insulin
NPH insulin Humulin® N

Novolin® N
$45

$45
$135

$135
Long-Acting Insulin Analogues
Insulin detemir Levemir® $95 $190
Insulin glargine Lantus® $95 $190
Covers meal times
Short-Acting Insulin
Regular insulin Humulin® R

Novolin® R
$45

$45
NA

$135
Rapid-Acting Insulin Analogues
Insulin aspart NovoLog® $105 $200
Insulin glulisine Apidra® $95 $180
Insulin lispro Humalog® $105 $200
Covers both (all through the day and meal times)
Premixed Human Insulin
70% NPH/30% regular insulin Humulin® 70/30

Novolin ® 70/30
$45

$45
$135

$135
50% NPH/50% regular insulin Humulin® 50/50 $45 NA
Newer premixed Insulin
70% insulin aspart protamine suspension/30% insulin aspart NovoLog® Mix 70/30 $105 $200
75% insulin lispro protamine suspension/25% insulin lispro Humalog® Mix75/25 $105 $200
50% insulin lispro protamine suspension/50% insulin lispro Humalog® Mix50/50 $105 $200

1 These drugs were included in the research studies.

2 Average Wholesale Price from Red Book, 2008. Price does not include the cost of needles or syringes.

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